Case

Treating musculoskeletal disorders in patients with comorbidities presents a significant clinical challenge, often requiring compromises that can impact patient outcomes. This case study illustrates the complexities of managing osteoarthritis in a patient w...

For families facing congenital heart disease (CHD) diagnoses, understanding complex anatomy and surgical plans can be overwhelming, leading to increased anxiety and potential misunderstandings. Extended reality (XR) offers a promising tool for improving com...

For young adults with hemophilia , the concept of 'normalization' in treatment can significantly impact their ability to pursue demanding careers and lifestyles. A case study highlights the importance of aligning treatment goals with individual patient aspi...

Adolescent obesity and type 2 diabetes represent a growing crisis, often resistant to conventional treatments. This case report suggests that Mazdutide, a GLP-1/GCGR dual agonist, may offer a novel therapeutic avenue for these complex patients, but the find...

Children with Alagille syndrome often have their growth misclassified using standard charts, leading to unnecessary anxiety and interventions. New condition-specific growth charts promise to provide a more accurate assessment, reducing the risk of over- or ...

Isolated splenic sarcoidosis poses a diagnostic puzzle, often mimicking other conditions. Clinicians must maintain a high index of suspicion and utilize biopsy when other causes of splenomegaly are ruled out.

A rare case highlights the risk of infected pseudoaneurysm formation following percutaneous closure device use, presenting with a subtle umbilical depression. Early recognition of such subtle signs can prevent significant morbidity and potential mortality.

Anaphylaxis following dextromethorphan is rare but can occur, requiring clinicians to maintain vigilance when patients present with acute allergic reactions. This case highlights the importance of detailed allergy workups, including skin testing, to identif...

In an era of automated urine analysis, critical diagnostic information can be missed. A focused look at the urine sediment may reveal the key to unlocking a diagnostic puzzle, especially when algorithms fail.

Early diagnosis of ADA2 deficiency is crucial to prevent irreversible organ damage; however, the disease's variable presentation often leads to diagnostic delays. Atypical presentations, such as early-onset neutropenia, further complicate and prolong the di...