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Berberine, a natural antimicrobial, shows enhanced potency against endodontic pathogens when delivered via polymeric nanoparticles. This targeted approach could improve root canal disinfection and reduce the need for aggressive chemical treatments.
Lipophosphonoxins show promise as broad-spectrum antibacterial agents, but their potential for clinical use hinges on overcoming significant hurdles. Further in vivo studies and toxicity assessments are critical before considering human trials.
Dental anxiety is more than just nerves; for some, it's a debilitating phobia that keeps them from essential care. Cognitive Behavioral Therapy (CBT) offers a promising alternative to sedation, addressing the root psychological causes of dental avoidance an...
Parents are increasingly seeking "natural" alternatives for their children's dental care, driving interest in phytotherapy. Clinicians need to understand the evidence, or lack thereof, to guide these families effectively and prevent potential harm.
Pediatric dentists are increasingly exploring phytotherapy, but the strength of evidence supporting its use remains unclear. This review highlights the need for more rigorous, randomized controlled trials to validate the efficacy and safety of herbal interv...
Using herbal remedies in pediatric dentistry requires careful communication with parents. Clinicians must understand both the potential benefits and documented risks before suggesting or agreeing to complementary treatments.
Neonatal cleft lip and palate complicate airway management during endotracheal intubation. A customized protective palatal obturator was evaluated in a randomized controlled trial for peri-intubation performance and safety in newborns undergoing cleft lip r...
In oral health, probiotic selection increasingly hinges on strain-level safety. A comprehensive assessment of Streptococcus salivarius OSTIA SALI-10 integrates genome screening for virulence and acquired antimicrobial resistance markers with phenotypic chec...
Oral microbiome probiotic Streptococcus salivarius OSTIA SALI-10 underwent a comprehensive safety evaluation spanning genomic, in vitro, and in vivo modalities, reporting no concerning signals across standard panels relevant to dental and periodontal contex...
In oral health and periodontal diseases, the probiotic Streptococcus salivarius OSTIA SALI-10 underwent a comprehensive safety evaluation integrating genome-scale screens for virulence and antimicrobial resistance and phenotypic assays spanning hemolysis, b...