Practice

Patients presenting with severe to profound sudden sensorineural hearing loss often face a poor prognosis, but early identification of specific risk factors can significantly guide patient counseling. Understanding these indicators allows clinicians to set ...

Patients suffering from recalcitrant supraspinatus tendinopathy may find relief with optimized shockwave therapy protocols. Understanding patient selection and proper technique are critical for successful outcomes with this non-invasive treatment.

The diagnostic odyssey for children with rare rheumatic diseases can be shortened by recognizing key clinical clues early. Improved diagnostic strategies and referral pathways are essential to reduce patient suffering and improve outcomes.

In cardiomyopathies, cardiac magnetic resonance T1 mapping and synthetic extracellular volume are influenced by age and sex, shifting normal ranges and the threshold for abnormality. Findings indicate clinicians should apply age- and sex-aware interpretatio...

In severe aortic regurgitation, applying the Genereux staging classification of extra-valvular cardiac damage predicted the likelihood and extent of left ventricular reverse remodeling after valve intervention. Higher stages were associated with attenuated ...

Respiratory syncytial virus in older adults and people with chronic disorders drives substantial winter morbidity. A Portuguese multisociety position recommends RSV vaccination for adults 60 years and older and for younger high-risk patients, endorses coadm...

In MASLD, aspirin use alone correlated with lower all-cause mortality and fewer liver-related events over roughly three years in multi-institutional data, without establishing causality. Signals appear most decision-relevant when cardiovascular indications ...

In coronary artery disease after percutaneous coronary intervention, an analysis of racial and ethnic variation in cardiovascular risks highlights heterogeneous profiles and outcome patterns that can shape secondary prevention . Differences in risk burden a...

In hereditary transthyretin amyloidosis with polyneuropathy, the siRNA therapy patisiran reduces hepatic TTR production, aiming to slow axonal injury. In individuals with V122I or T60A variants, results indicate neuropathy can stabilize or improve on treatm...

Amyotrophic lateral sclerosis limits energy and mobility, making traditional trial operations taxing. Participants value altruism but resist avoidable burden. The key finding: reduce travel, compress or replace in-person visits, and enable remote or at-home...